MITOTANE Dosage and Mechanism

 Mitotane is a potent cancer medicine which is sold under the brand name LYSODREN. It is used in the treatment of patients with advanced adrenal cortical carcinoma, which is basically a kind of cancer of the outer layer of the adrenal gland. Mitotane is a cytotoxic agent which is used when cancer is inoperable, either functional or non-functional and relapsed. 

Patients with adrenal cortical carcinoma are low; hence it is considered 'rare', and LYSODREN is taken as an orphan medicine for this rare disease. It is available in India, and lysodren's price is economical and can be easily purchased by any authorized supplier against a valid prescription.

How to take Mitotane?

It is available as 500mg tablets, and the initial dose is 2 g to 6 g orally daily, in three or four divided doses, taken with meals containing fatty foods. Increase the dose incrementally to achieve a blood concentration of 14 to 20 mg/l, or as tolerated, and the levels of the active substance in the blood should be monitored frequently. 

Levels above 20 mg/L may cause severe side effects without increasing the medicine's effectiveness. The medicine should be taken till the time it is effective and must be withdrawn if there are any side effects. Indian Pharma Network is among the reliable platforms which facilitate patients' connection with genuine pharmaceutical suppliers, wholesalers, and dealers. To know more details about the cost of MITOTANE in India, contact us at https://indianpharmanetwork.in/contact-us/ 

There is limited information on the use of Lysodren in children, but a daily starting dose of 1.5 to 3.5 g per square meter of body surface area is recommended.

How does MITOTANE work?

Mitotane is a white granular solid composed of clear, colorless crystals. It is tasteless and has a slightly pleasant aromatic odour. Steroid hormones are produced by the cortex of the adrenal gland. When this area develops cancer, levels of these hormones can increase, which causes the symptoms of the disease. The active substance in Lysodren, Mitotane, is thought to work by inhibiting cells in the adrenal gland from working properly and by damaging their mitochondria, there is a reduction in some steroid hormones. It may also alter the breakdown of these hormones. Together, these effects reduce the levels of the hormones in the body, improving the symptoms of the disease. But the exact mechanism of this cytotoxic agent is still unknown. 

Patients taking recommended doses of Mitotane can get benefits fighting against this cancer, and Mitotane 500 mg tablets at economical prices can be obtained through Indian Pharma Network.

For more details about Mitotane, call us at our toll-free number, 18008891064; we will be happy to help you.