- Availability in India
Blinatumomab is a cancer medicine that is sold under the brand name Blincyto. It is used to treat a blood cancer called B-precursor acute lymphoblastic leukemia in patients of age one year and above. Its usage is accompanied by patients whose cancer has relapsed or has not improved with previous treatment. It can also be used in these patients as part of ‘consolidation therapy’ to improve the diminution of cancer. Blincyto is used in patients who have the protein CD19 on their cancer cells and are ‘Philadelphia-chromosome-negative’ (Ph-negative), which means that the patient’s cancer cells do not have an abnormal chromosome called the Philadelphia chromosome.
It is available in India for use and can be supplied by an approved generic medication supplier.
We are the most reliable suppliers to buy Blincyto 38.5 mcg at economical prices.
It can easily be purchased as Blincyto's price in India is pocket friendly and can only be obtained with a prescription, and treatment should be started by a medical specialist who has experience in the treatment of patients with cancers of the blood. It is available in injections as 35 mcg lyophilized powder in a single dose via injection is available for Administration. Before the treatment, body weight is monitored, and the dose is calculated on the basis of weight. It is given by dripping the vein, and the infusion is done intravenously only by a pump device.
For reconstitution, add 3 mL of preservative-free Sterile Water for Injection of USP directly into the walls of BLINCYTO, and the resulting final concentration is 12.5 mcg/mL. The prepared infusion is gently swirled, and excess foam is avoided. If there is any particulate matter or any sort of discoloration is observed, the batch of prepared BLINCYTO must be discarded and should not be used. After preparation, the prepared BLINCYTO-infused bag must be continuously induced over a period of 24 or 48 hours.
For treatment of relapsed or refractory B-precursor ALL, the dose depends on the patient’s weight. Blincyto is infused continuously for four weeks as part of the treatment cycle. Each cycle is separated by an interval after a two-week treatment. Patients are treated with an additional three cycles of BLINCYTO and have no signs of cancer after two cycles if the benefits outweigh the risks for the patient.
It can be obtained from various suppliers, and you can also buy BLINCYTO online from
- Method Of Action
In B-precursor ALL, certain cells that give rise to a type of white blood cell called B cells multiply too quickly, and they eventually replace normal blood cells with abnormal cells. The active substance in Blincyto is blinatumomab which is an antibody that has been designed to attach to a CD19( a protein) found on B cells, including ALL cells. It also attaches to a protein (CD3) in T cells. T cells are another type of white blood cell.
Hence, Blincyto acts as a ‘bridge’, bringing T cells and B cells together. It causes the T cells to release substances that kill the cancerous B cells eventually.
People who have blood cancer of this kind can get this medicine against a prescription from any of the suppliers at economical prices, as the cost of BLINCYTO in India, is budget-friendly.
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- Adverse Reactions and Side Effects
BLINCYTO injection can cause some side effects. Most common adverse reactions associated with BLINCYTO are infections, fever, infusion-related reactions, headache, febrile neutropenia, constipation, nausea, diarrhea, vomiting, anemia (low red blood cell counts), edema (swelling because of fluid retention), neutropenia (low levels of neutrophils, a type of white blood cell), leucopenia (low levels of white blood cell), thrombocytopenia (low platelet count), blood tests showing changes in liver function, tremor (shaking), back pain, chills, low blood pressure, low levels of immunoglobulins (antibodies), cytokine release syndrome (a life-threatening condition that can cause fever, vomiting, shortness of breath, pain and low blood pressure), rapid heartbeat, insomnia (difficulty sleeping), pain in the arms and legs, abdominal (belly) pain, cough and rash.
Most serious reactions associated with BLINCYTO include neutropenia with or without fever, infections, cytokine release syndrome, and tumor lysis syndrome.
Apart from all these side effects, it is very efficient if used properly under the supervision of an expert doctor.
Moreover, BLINCYTO injection price in India is economical, and it can be purchased at reasonable rates. For more detail on the adverse effects of the drug, Call/WhatsApp (+91) 8130290915 or Email us on info@ikrispharmanetwork.com
- Drug Interactions
There are no formal drug interaction studies that have been conducted with BLINCYTO. Starting the treatment of BLINCYTO causes the transient release of cytokines which may suppress CYP450 enzymes. During the first 9 days of the first cycle and the first 2 days of the second cycle in patients who are receiving concomitant CYP450 substrates, there are the highest drug-drug interaction risk, particularly those with a narrow therapeutic index. In these patients, monitor for toxicity (e.g., warfarin) or drug concentrations (e.g., cyclosporine). Adjust the dose of the concomitant drug as needed.
- USE IN SPECIFIC POPULATION
● Pregnancy- BLINCYTO may cause fetal harm, including B-cell lymphocytopenia, when
administered to a pregnant woman according to their method of action. There is no data on the
use of BLINCYTO in pregnant women, but it is advised to pregnant women not to use it because
it may cross the placental barrier shown in animal studies and may cause potential risks to a fetus.
The background rate of major birth defects and miscarriage is unknown for the indicated
population. It is easily available as you can buy BLINCYTO online, so all the side effects and
use must be understood properly and used in an efficient and safer way.
● Lactation- There is no information regarding the presence of blinatumomab in human milk or the effects on the breastfed infant, or the effects on the production of milk. Because of the fact many drugs are excreted in human milk and because of the potential for serious adverse reactions in nursing infants from BLINCYTO, including B-cell lymphocytopenia, it is advised to patients not to breastfeed during and for at least 48 hours after treatment with BLINCYTO.
Full restrictions can be seen on the package leaflet. To know more about BLINCYTO price in India you can email us at info@indianpharmanetwork.in
- STORAGE
Each BLINCYTO package contains one BLINCYTO 35 mcg single-dose vial containing a sterile,
preservative-free, white to off-white lyophilized powder and one intravenous Solution stabilizer of 10 mL single-dose glass vial containing a sterile, preservative-free, colorless to a slightly yellow, clear solution. It is clearly mentioned not to use the IV Solution Stabilizer to reconstitute BLINCYTO. BLINCYTO and IV Solution Stabilizer vials in the original package are stored and refrigerated at 2°C to 8°C (36°F to 46°F) and protected from light until the time of use. Do not freeze. Store and transport the prepared intravenous bag containing BLINCYTO solution for infusion at 2°C to 8°C (36°F to 46°F) conditions. Ship in packaging that has been validated to maintain the temperature of the contents at 2°C to 8°C (36°F to 46°F).
Indian pharma network has expertise in cold chains, so the drug is exported in a safer manner and delivered more efficiently. We serve our patients the best thing possible, and to know more about BLINCYTO cost you can visit us at Contact us: Ikris Pharma Network | Toll-Free:- 1800 889 1064
- DESCRIPTION
It is a bispecific CD19-directed CD3 T-cell engager that binds to CD19 and CD3. BLINCYTO is
produced in Chinese hamster ovary cells. It contains 504 amino acids, which have a molecular weight of approximately 54 kilodaltons. Each BLINCYTO package contains 1 vial BLINCYTO and 1 vial IV Solution Stabilizer. BLINCYTO is supplied in a single-dose vial as a sterile, preservative-free, white to off-white lyophilized powder for intravenous Administration. Each single-dose vial of BLINCYTO contains 35 mcg drug, and the Blincyto injection price is pocket efficient. It also contains citric acid monohydrate (3.35 mg), lysine hydrochloride (23.23 mg), polysorbate 80 (0.64 mg), trehalose dihydrate (95.5 mg), and sodium hydroxide to adjust pH to 7.0. After reconstitution with 3 mL of preservative-free Sterile Water for injection, USP, the resulting concentration is 12.5 mcg/mL blinatumomab. IV Solution Stabilizer is supplied in a single-dose vial which is sterile, preservative-free, colorless to a slightly yellow, clear solution.
Each single-dose vial of IV Solution Stabilizer contains citric acid monohydrate (52.5 mg), lysine hydrochloride (2283.8 mg), polysorbate 80 (10 mg), sodium hydroxide to adjust pH to 7.0, and Water for injection. To know more about BLINCYTO price, you can Call/WhatsApp us at (+91 9310090915)
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